I've never used the msd so no personal experience, but I figured for 7 bucks I would get the best. Here's a chunk of a post from bajaron.
I carry 2 wires set versions, MSD (RED) and Accel (Black). They are of similar construction using the same process to get spark from the coil to your Spark Plug (Low resistance Spiral Wound Copper Alloy Wire instead of the OEM High resistance Carbon Impregnated Core). The Accel wire is thicker (8.8mm to 8.5mm and the Accel outer skin is more heat and cut resistant than the MSD wire). However, both will perform very will on your Spyder.
I think the accel wires greater heat resistance is what convinced me, what with all the fun people have with heat build up "under her skirt"