I had a thick hex-head bolt (3/8 or 7/16, I dunno) poke its way through the tread of a front Kenda on my 2015. A tire shop dismounted and inside-patched the hole, and it now runs just fine. That was several tens of thousands of miles ago, and it's still running with no ill effects. I now have over 66,500 miles on those OEM Kendas, they still run smooth enough, and have lots of tread left. Just the other day I punched it up to 110mph briefly, with no handling problems (just pay real close attention!).
YMMV.