I'm at a slight disadvantage given my weight-- at 280 lbs right now, it don't matter WHAT I sit on, I put a lot of pressure on my seat... and my seat :joke:.
In pursuit of a better seat, I've progressively added the following, at great expense, to my RS (with the equivalent miles I could ride before pain):
Stock seat: 50-60 miles
Beadrider: 75-100 miles
Risers: 100 miles
Floorboards and Ultimate Seat: 150+ miles
... and just this weekend, an Airhawk R (the new model with the bigger cutout for the, ummm, gentlemenly parts): I rode *220* miles on Saturday; 200 miles without pain, the last 20 were pretty bad but I was almost home at that point; on a long trip, 100 mile hops would be perfectly sustainable.
Out of all of those options, somewhat ironically the biggest difference was made by the cheapest item, the Beadrider. Yeah, it's not plush softness, but it move the butt around enough to keep pressure points from forming. That matters a great deal.
The risers and floorboards allow me to move my seating position around, stretch the legs, unhinge my knees, etc. That makes a big difference on a long ride.
The Ultimate Seat is a wonderful product, albeit expensive (and only for the RS right now, so of no help to the OP). Alas, at my weight I could use a bit more padding than it came with; oh well, incentive to lose weight, right?
The Airhawk R... I'm not sold yet, I don't quite know if it's a substantial improvement over the Beadrider (yes, I got a lot of miles out of it this weekend, but I think I could get the same out of the beads with the Ultimate Seat/floorboard setup). The good news about the Airhawk is it comes with a *SIXTY* day guarantee-- I plan on riding with it a lot over the next few weeks, swapping it and the Beadrider out to get a good comparison test.
Next purchase is some padded underwear... I'm hoping the helps a bit, too.
Anyway... good luck with the seat hunt!