As many answers as there are belly-buttons. Why not just ask about octane or the best oil?

OK, you asked for it, here are some more relatively usless contributions.
1. Since the Spyder manual discusses engine braking, I would expect the trans is designed to take it. I have done it all my driving and riding life, and I never busted a transmission yet. Burnouts, on the other hand, may not be so good...
2. RPM will impact mpg, but not necessarily in a linear fashion. Either too low or too high can ruin mileage. Biggest offender is actually the speed with whichh you apply the throttle and your riding (driving) smoothness, according to the old Shell mileage run experts.
3. Oil life is significantly better with highway miles as opposed to short runs or stop-and-go. Hard to put a number on it. The oil life also varies with the oil used and the climate conditions. Under warranty, I would stick with the recommended mileage between changes. After that, I think you could get significantly more with full synthetic oil and a lot of highway miles. They put all these electronic gizmos on the Spyder, but there is no oil life indicator, like in many modern cars. Guess the computer is too busy monitoring bulb loads.
4. I think the tire pressure is more static, and depends the most on the tire construction, and vehicle load conditions. Most touring motorcycles carry at least two recommended tire pressures, one with passenger or load, and one without. They are smaller than Spyder or auto tires, so will be affected more, but I would think the same principles apply.
-Scotty