My bank tracks my credit card history and denies the purchase if out of line with my buying history. Over the years, my card has been shutdown several times and has been spot on with each denial. I receive a phone call alert when this happens.
Other things that I have done are lowering my credit and cash advance limits. I also have a card for at home/in town and another for traveling/out of town.
If your card has fraudulent activity and you receive an alert, you can many times go online and see where it has been used or the attempted use. The last time I was able to go right to the individual who tried to use it. They were shocked to find out that I was able to track them down. Priceless.