At least try a Bead Rider
Have you tried an Ultimate BeadRider seat cover? I have one and just did a 1,500 mile 30 hour leg on part of our recent ten day trip (trying for an IBA Bun Burner 1500 cert). I had one and I know it helped me, but riding buddy Jerry just bought one and ended up taking it off during the trip. Sold it to a GOS at the bottom of the Tail of the Dragon, I've heard she really liked it. Again, a matter of personal preference, but it wouldn't hurt to try it. Mine stays on full time now, going for a BBG later this week.
I think it gives your tired, hot butt a massage, allows cool air to vent between you and the seat, and has kept my jeans dry during some spotty showers.
Last July 5th I did a SS1000 through Iowa and never got a hot butt.
Just installed an Ultimate Tall Boy on my RS
My problem is I am 6'5" and 270lbs and have no butt. I'm sure there are plenty of others out there with the same problem! The OEM seat just caused two points of pain after two hours. The Ultimate seat is very different. At first I wondered if it was too hard, but like suggested I am going to break it in, give it maybe 1000 miles before final judgement. There is no pain in the first two hours though, and the backrest is very welcome. It definitely feels stiff out of the box. I also tried gel pads, beads, airhawk, etc. nothing worked. I think the Ultimate seat is a little wider, maybe that is helping too.